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Abstract: SA-PO1101

Sleep Duration and Kidney: Does Weekend Sleep Matter?

Session Information

Category: CKD (Non-Dialysis)

  • 2301 CKD (Non-Dialysis): Epidemiology, Risk Factors, and Prevention

Authors

  • Wu, Chia-Chao, Tri-Service General Hospital Department of Internal Medicine, Taipei, Taiwan
  • Lu, Kuo-Cheng, Taipei Tzu Chi Hospital, Taipei, Taiwan
Background

Weekend sleep duration is linked to health issues, including mortality. However, how weekend sleep duration can impact chronic kidney disease (CKD) still needs to be understood. Therefore, we aimed to analyze how weekend sleep duration is associated with kidney function.

Methods

Data were obtained from the 2017-2018 National Health and Nutrition Examination Survey. We included 5,362 study participants and categorized them into nine subgroups by sleep duration (≤6 hours, 6–9 hours, and ≥9 hours) on weekdays and weekends and analyzed for the respective association with renal function using multivariable linear regression.

Results

Weekend sleep duration for 9 hours or more was associated with decreasing estimated glomerular filtration rate (eGFR) levels by 2.8 to 6.4 ml/min/1.73 m2 among people with long to short weekday sleep duration compared with short weekday and weekend sleep durations (control group) after adjusting for demographic characteristics, body measurement, sleep quality, smoking, and comorbidities. The study population with short weekday sleep duration (sWK) and long weekend sleep duration (lWKD) had the most significant decline in eGFR. For the study population with sWK, eGFR level significantly decreased by 1.1 ml/min/1.73 m2 as sleep duration on weekends increased by one hour. Therefore, weekday and weekend sleep duration should both be considered when investigating the relationship between sleep duration and CKD.

Conclusion

Longer weekend sleep duration was linked to a decrease in eGFR levels. It warrants further study to confirm the causal association and clarify the mediators

Funding

  • Government Support – Non-U.S.