Abstract: SA-PO354
Is Interdialytic Weight Gain Really All Fluid? A Longitudinal Study on Short Term Variability of Bioimpedance-Derived Normohydration Weight in Hemodialysis Patients
Session Information
- Hemodialysis and Frequent Dialysis: CV and Risk Prediction
November 05, 2022 | Location: Exhibit Hall, Orange County Convention Center‚ West Building
Abstract Time: 10:00 AM - 12:00 PM
Category: Dialysis
- 701 Dialysis: Hemodialysis and Frequent Dialysis
Authors
- Waller, Maximilian, Klinik Favoriten, Wien, Wien, Austria
- Krenn, Simon, Austrian Institute of Technology GmbH, Wien, Wien, Austria
- Mussnig, Sebastian, Medizinische Universitat Wien, Wien, Wien, Austria
- Hecking, Manfred, Medizinische Universitat Wien, Wien, Wien, Austria
Group or Team Name
- HD Research & Co.
Background
Hemodialysis (HD) aims at reaching normohydration. The patient’s weight measured predialysis and the desired target weight postdialysis usually determine the ultrafiltration volume, following the assumption that weight gain from the previous HD session (IDWG) consists of excess fluid.
Methods
Longitudinal boimpedance spectroscopy (BIS) measurements with the Body Composition Monitor (BCM, Fresenius Medical Care Germany, v3.2) were obtained predialysis in 14 consecutive HD-sessions from 25 patients treated at the Chronic Hemodialysis Unit of Vienna General Hospital between October and December 2021. Short term variability of BIS derived parameters of fluid status was analyzed in an explorative fashion.
Results
The normohydration weight was 78.4±13.9 kg on average ± standard deviation (SD) and varied longitudinally for each patient, with the intra-patient SD ranging from 0.36 to 2.24kg (average: 0.8 kg). When the predialysis weight increased from one HD session to the next, the normohydration weight increased also, indicating that the patient had not only gained fluid (Figure 1).
Conclusion
Under the assumption that the BCM yields adequate results, and even if the target weight was set to perfect normohydration with 0L fluid overload remaining postdialysis, any weight gain above the previous predialysis weight will likely not consist of fluid alone. These results suggest that the target weight should not be fixed.
Figure 1