Abstract: SA-PO363
The Clinical Outcomes of Blood Pressure in Maintenance Hemodialysis Patients: A Single Center Study
Session Information
- Hemodialysis and Frequent Dialysis: CV and Risk Prediction
November 05, 2022 | Location: Exhibit Hall, Orange County Convention Center‚ West Building
Abstract Time: 10:00 AM - 12:00 PM
Category: Dialysis
- 701 Dialysis: Hemodialysis and Frequent Dialysis
Authors
- Luo, Yuan, The Second Affiliated Hospital of Nanjing Medical University, Nanjing, China
- Zhuang, Bing, The Second Affiliated Hospital of Nanjing Medical University, Nanjing, China
- Wei, Guiling, The Second Affiliated Hospital of Nanjing Medical University, Nanjing, China
- Ye, Hong, The Second Affiliated Hospital of Nanjing Medical University, Nanjing, China
- Yang, Junwei, The Second Affiliated Hospital of Nanjing Medical University, Nanjing, China
Background
The prevalence of hypertension among patients on dialysis and the degree to which it is controlled is difficult to ascertain，and the relationship between blood pressure (BP) and clinical outcomes among hemodialysis patients is complex and incompletely understood. This study sought to assess the relationship between interdialytic blood pressure and clinical outcomes.
Methods
We enrolled 456 maintenance hemodialysis patients from January to May 2022 in our center, measured interdialytic office blood pressure and volume load，and the demographic characteristics，duration of dialysis, laboratory tests, as well as the cardiac function were collected and analyzed.
Results
A total of 456 patients were included in the investigation with the mean age of 58.3±12.1 years old and 58.5% were male. The most common cause of dialysis was diabetic nephropathy (32.3%) and the second was hypertensive nephropathy (21.8%). Only 30.1% of the population blood pressure was controlled, under 140/90mmHg and over 100/60mmHg. 29.4% of the patients BP was more than 140/90mmHg. 59.2% of the study population used 1-2 antihypertensive drugs, and the most commonly used antihypertensive drugs were calcium antagonists. We observed the relationship between blood pressure and duration of dialysis and and found a positive correlation with blood pressure with dialysis age (P<0.0001). There is also a positive correlation between LV wall thickness and systolic blood pressure, with thicker LV walls in patients with high systolic blood pressure. We measured the blood pressure of the patients before and after the six-minute walk test. We found that after the exercise, most of the patients had an increase in blood pressure, but 33.8% of the patients had a decrease in blood pressure. 59.8% of patients with a decrease in blood pressure used calcium antagonists (P<0.0001).
Conclusion
Although most hypertensive patients were on antihypertensive drugs, the proportion of patients with interdialytic blood pressure under 140/90mmgHg is low. Hypertension is also associated with cardiac remodeling, with thicker left ventricular wall in patients with higher blood pressure.
Funding
- Government Support – Non-U.S.