Abstract: FR-PO938
Relationship of Light-Intensity and Moderate-to-Vigorous Intensity Physical Activity Habits for Kidney Dysfunction: A General Population Cohort Study
Session Information
- CKD: Epidemiology, Risk Factors, Prevention - II
November 04, 2022 | Location: Exhibit Hall, Orange County Convention Center‚ West Building
Abstract Time: 10:00 AM - 12:00 PM
Category: CKD (Non-Dialysis)
- 2201 CKD (Non-Dialysis): Epidemiology‚ Risk Factors‚ and Prevention
Authors
- Sakurai, Goro, Kanazawa Daigaku, Kanazawa, Ishikawa, Japan
- Toyama, Tadashi, Kanazawa Daigaku, Kanazawa, Ishikawa, Japan
- Hara, Akinori, Kanazawa Daigaku, Kanazawa, Ishikawa, Japan
- Yamamura, Yuta, Kanazawa Daigaku, Kanazawa, Ishikawa, Japan
- Nakagawa, Shiori, Kanazawa Daigaku, Kanazawa, Ishikawa, Japan
- Oshima, Megumi, Kanazawa Daigaku, Kanazawa, Ishikawa, Japan
- Miyagawa, Taro, Kanazawa Daigaku, Kanazawa, Ishikawa, Japan
- Ogura, Hisayuki, Kanazawa Daigaku, Kanazawa, Ishikawa, Japan
- Kitajima, Shinji, Kanazawa Daigaku, Kanazawa, Ishikawa, Japan
- Sakai, Norihiko, Kanazawa Daigaku, Kanazawa, Ishikawa, Japan
- Shimizu, Miho, Kanazawa Daigaku, Kanazawa, Ishikawa, Japan
- Wada, Takashi, Kanazawa Daigaku, Kanazawa, Ishikawa, Japan
- Iwata, Yasunori, Kanazawa Daigaku, Kanazawa, Ishikawa, Japan
Group or Team Name
- Department of Nephrology and Laboratory Medicine, Kanazawa University
Background
There are limited studies considering exercise intensities and their frequencies in relation to kidney dysfunction.
Methods
A community-based historical cohort study was conducted including Japanese general people aged ≥ 40 years. Participants were divided into four categories according to the combination of their exercise habits: regular light-intensity physical activity (R-LPA: 1.5 to 3.0 metabolic equivalents [METs] at least 60 minutes a day) and occasional moderate-to-vigorous physical activity (O-MVPA: > 3.0 METs at least 30 minutes twice a week). The outcome was the incidence of a 40% decrease in estimated glomerular filtration rate (eGFR) from baseline. Cox proportional hazards models were used to examine the association of exercise habits.
Results
A total of 72,999 people were included. During the mean follow-up of 5.9 years, 2,989 (4.1%) participants achieved the outcome. Compared to the people with neither R-LPA nor O-MVPA, the adjusted hazard ratios were 0.94 (95% CI: 0.85, 1.03; p = 0.182) for R-LPA alone, 0.97 (95% CI: 0.85, 1.10; p = 0.618) for O-MVPA alone, and 0.83 (95% CI: 0.76, 0.91; p < 0.001) for a combination of R-LPA and O-MVPA. There was a significant interaction between sex and exercise habits.
Conclusion
In general people, a combination of R-LPA and O-MVPA was associated with a lower risk of kidney dysfunction compared with no exercise habit. Future studies are warranted to determine the exercise intensity and duration that protects kidney function.