Kidney Week

Abstract: TH-PO719

Association Between Social Support and Hospitalization Risk Among Adults With CKD

Session Information

• Diversity and Equity in Kidney Health - I
  November 03, 2022 | Location: Exhibit Hall, Orange County Convention Center‚ West Building
  Abstract Time: 10:00 AM - 12:00 PM

Category: Diversity and Equity in Kidney Health

• 800 Diversity and Equity in Kidney Health

Authors

• Alvarado, Flor, Tulane University School of Medicine, New Orleans, Louisiana, United States

Flor Alvarado,

• Geng, Siyi, Tulane University School of Public Health and Tropical Medicine, New Orleans, Louisiana, United States

Siyi Geng,

• Chen, Jing, Tulane University School of Medicine, New Orleans, Louisiana, United States

Jing Chen,

• He, Hua, Tulane University School of Public Health and Tropical Medicine, New Orleans, Louisiana, United States

Hua He,

• Rivera, Eleanor, University of Illinois Chicago UI Health, Chicago, Illinois, United States

Eleanor Rivera,

• Saunders, Milda R., The University of Chicago Medicine, Chicago, Illinois, United States

Milda R. Saunders,

• Shah, Vallabh O., University of New Mexico School of Medicine, Albuquerque, New Mexico, United States

Vallabh O. Shah,

• Nelson, Robert G., National Institute of Diabetes and Digestive and Kidney Diseases, Phoenix, Arizona, United States

Robert G. Nelson,

• Jaar, Bernard G., Johns Hopkins Medicine, Baltimore, Maryland, United States

Bernard G. Jaar,

• Unruh, Mark L., University of New Mexico School of Medicine, Albuquerque, New Mexico, United States

Mark L. Unruh,

• Ricardo, Ana C., University of Illinois Chicago UI Health, Chicago, Illinois, United States

Ana C. Ricardo,

• Crews, Deidra C., Johns Hopkins Medicine, Baltimore, Maryland, United States

Deidra C. Crews,

• Anderson, Amanda Hyre, Tulane University School of Public Health and Tropical Medicine, New Orleans, Louisiana, United States

Amanda Hyre Anderson,

• He, Jiang, Tulane University School of Medicine, New Orleans, Louisiana, United States

Jiang He,

Background

Adults with chronic kidney disease (CKD) have a higher risk of hospitalization than the general population. We evaluated the association of social support, a potentially modifiable factor, with hospitalization risk among adults with CKD.

Methods

This was a prospective cohort study of adults with mild to moderate CKD enrolled in the Chronic Renal Insufficiency Cohort (CRIC) Study. Social support was assessed using the six-item Lubben Social Network Scale (LSNS-6). The summary score ranged from 0-30. A score <12 was considered “at-risk” for social isolation, reflecting low social support. The LSNS-6 was administered between 2013 to 2018, which was considered the baseline for the present study; and follow-up occurred until death, study withdrawal, or May 2020. Hospitalizations were ascertained based on participant self-report and review of medical records and were recorded as the number of hospitalizations. Number of hospitalizations per 1000 person-years was calculated. Counts of hospitalization by isolation risk status were assessed using a Poisson regression model controlled for the duration of follow-up.

Results

Among a subset of 1155 CRIC participants with baseline LSNS-6 assessments available, mean age was 69, 39% were female, 16% were Hispanic, 41% non-Hispanic Black, 41% non-Hispanic White, mean eGFR was 55 mL/min/1.73m², and 30% were considered at-risk for social isolation. There were 4015 hospitalizations, and the maximum follow-up period was 6.7 years. In unadjusted analyses, an increased risk of all-cause hospitalization was found among those at-risk for social isolation in the whole cohort and in all racial/ethnic subsets (Table). After multivariable adjustment for other sociodemographic variables, the risk remained for Hispanic participants (Incidence Rate Ratio 2.09; 95% CI 1.62-2.68).

Conclusion

Low social support was associated with increased all-cause hospitalization risk among Hispanic individuals with CKD.

Funding

• NIDDK Support