Kidney Week

Abstract: PO0864

Body Fat Mass Plays an Important Role in Over- or Underestimation of Bioimpedance Spectroscopy-Based Dry Weight for Patients with Hemodialysis

Session Information

• Fluid, Electrolytes, and Clinical Events with Dialysis: Getting to the "Heart" of the Matter
  November 04, 2021 | Location: On-Demand, Virtual Only
  Abstract Time: 10:00 AM - 12:00 PM

Category: Dialysis

• 701 Dialysis: Hemodialysis and Frequent Dialysis

Authors

• Choi, Dae Eun, Chungnam National University School of Medicine, Daejeon, Daejeon, Korea (the Republic of)

Dae Eun Choi, MD, PhD

• Kim, Hae Ri, Chungnam National University Sejong Hospital, Sejong, Korea (the Republic of)

Hae Ri Kim,

• Jeon, Jae wan, Chungnam National University Sejong Hospital, Sejong, Korea (the Republic of)

Jae wan Jeon,

• Shin, Jin Ah, Chungnam National University School of Medicine, Daejeon, Daejeon, Korea (the Republic of)

Jin Ah Shin,

• Han, Soo hyun, Chungnam National University School of Medicine, Daejeon, Daejeon, Korea (the Republic of)

Soo hyun Han,

• Hwang, Haet Bit, Chungnam National University School of Medicine, Daejeon, Daejeon, Korea (the Republic of)

Haet Bit Hwang,

• Lee, Eu Jin, Chungnam National University School of Medicine, Daejeon, Daejeon, Korea (the Republic of)

Eu Jin Lee,

• Na, Kiryang, Chungnam National University School of Medicine, Daejeon, Daejeon, Korea (the Republic of)

Kiryang Na,

• Lee, Kang Wook, Chungnam National University School of Medicine, Daejeon, Daejeon, Korea (the Republic of)

Kang Wook Lee,

Background

Accurate dry weight (DW) estimation is important for hemodialysis patients. Although bioimpedance spectroscopy (BIS) is commonly used to measure DW, the BIS-based DW frequently differs from the clinical DW.

Methods

We analyzed the characteristics of patients whose BIS-based DWs were over- and underestimated. In this retrospective cohort study, we evaluated 1,555 patients undergoing maintenance hemodialysis in Chungnam National University Hospital. The gap (DW_CP-BIS) was calculated by comparing the BIS and clinical DWs.

Results

We analyzed the clinical characteristics of patients with positive (n = 835) and negative (n = 720) gaps. Compared with other patients, the DW_CP-BIS-positive group was taller, had higher extracellular water (ECW) level and extracellular/intracellular water index (E/I); and had lower weight, body mass index (BMI), lean tissue index (LTI), fat tissue index (FTI), fat mass (FAT), and adipose tissue mass (ATM), as well as lower levels of hemoglobin, total protein, albumin, and phosphorous. The DW_CP-BIS-negative group exhibited higher levels of hemoglobin, total protein, albumin, and phosphorous, as well as elevated BMI, FTI, FAT, and ATM; however, it had lower height, ECW, and E/I. Linear regression analysis revealed that FAT significantly predicted DW_CP accuracy.

Conclusion

The clinical DW of patients with malnutrition and a low fat mass tended to be underestimated, while the clinical DW of patients with comparatively large fat reserves tended to be overestimated. These characteristics of dialysis patients will aid in the correction of BIS-associated DW errors