Kidney Week

Abstract: SA-PO1045

Dietary Phosphorus and Protein Intake in a Diverse Cohort of Hemodialysis Patients

Session Information

• Diet and Nutrition: Clinical
  October 27, 2018 | Location: Exhibit Hall, San Diego Convention Center
  Abstract Time: 10:00 AM - 12:00 PM

Category: Health Maintenance, Nutrition, and Metabolism

• 1302 Health Maintenance, Nutrition, and Metabolism: Clinical

Authors

• Tortorici, Amanda R., UC Irvine Medical Center, Irvine, California, United States

Amanda R. Tortorici,

• Rhee, Connie, University of California Irvine, Huntington Beach, California, United States

Connie Rhee,

• Kalantar-Zadeh, Kamyar, University of California Irvine, School of Medicine, Orange, California, United States

Kamyar Kalantar-Zadeh,

• Streja, Elani, Harold Simmons Center for Kidney Disease Research and Epidemiology, Orange, California, United States

Elani Streja,

• Juarez, Kimberly Michelle, University of California Irvine, Huntington Beach, California, United States

Kimberly Michelle Juarez,

• Novoa, Alejandra, UC Irvine Health, Orange, California, United States

Alejandra Novoa,

• Nakata, Tracy, UC Irvine, Orange, California, United States

Tracy Nakata,

• You, Amy Seung, University of California, Irvine, Orange, California, United States

Amy Seung You,

Background

We sought to determine whether dietary phosphorus (P) and protein intake in hemodialysis (HD) patients varies across race/ethnicity.

Methods

We identified 407 patients from the “Malnutrition, Diet, and Racial Disparities in Chronic Kidney Disease” (MADRAD) study, a racially/ethnically diverse prospective hemodialysis cohort who underwent food frequency questionnaire assessment. We compared baseline daily dietary intake of P, protein, and ratios of P/protein, P/kcal, as well as protein/kcal across racial/ethnic groups using one-way ANOVA and Bonferroni post hoc analyses.

Results

Blacks had the highest average daily intake of dietary P (882.7±765.7mg) and protein (62.8±54.5g), while patients of other race/ethnicities had the highest ratio of protein/kcal (0.049±0.01g/kcal). The differences in P/protein intake across racial/ethnic groups were significant, such that Hispanics had significantly higher ratios than Blacks and others: 17.2±5.3, 14.4±2.7, and 13.6±2.9mg/g, respectively; p<0.01. Hispanics also had the highest ratio of P/kcal (0.71±0.16mg/kcal). The differences in dietary protein/kcal ratios across racial/ethnic groups were also significant, such that Hispanics had significantly lower intake than Blacks and those of other race/ethnicity: 0.043±0.01, 0.048±0.01, 0.049±0.01, respectively; p<0.01.

Conclusion

These data suggest that, compared to other racial/ethnic groups, Hispanic HD patients’ dietary P intake relative to protein intake is higher, whereas their dietary protein intake relative to their total caloric intake is lower. Further studies are needed to determine the specific dietary sources of P among HD patients of varying race/ethnicity, and whether these variations may have a differential impact on their health and survival.

Funding

• NIDDK Support