Abstract: SA-PO031
Long-Term Outcome of Kidney Transplant Recipients Admitted to the Intensive Care Unit
Session Information
- Transplantation: Clinical Outcomes
October 27, 2018 | Location: Exhibit Hall, San Diego Convention Center
Abstract Time: 10:00 AM - 12:00 PM
Category: Transplantation
- 1802 Transplantation: Clinical
Author
- El Agroudy, Amgad E., College of Medicine and Medical Sciences, Arabian Gulf University, Manama, capital, Bahrain
Background
The goal of this study was to evaluate the course and outcome of kidney transplant (KT) recipients admitted to ICU.
Methods
We reviewed the data of all adult renal transplant recipients who are admitted to the ICU at our center, between 1997 and 2017 that included the demographic features, causes of end-stage renal disease (ESRD), causes of admission, time between transplantation and admission and ICU courses and outcome. Among 379 KT followed up in our center, 60 patients were admitted to ICU and were categorized to early (during first 3 months; n=28); intermediate (3–12 months; n=7); and late (12 months and afterwards, n=25).
Results
The rate of ICU admission was 15.9% and the mean age was 48.3 ± 12.6 years. The main cause of admissions was surgical complication (71%) in early group and infection (57% and 80%) in later groups, respectively. Mortality on discharge was significantly higher in late admission (52%) (p=0.0001) and the leading cause of death in all groups was sepsis (89%). Twenty patients required ventilator that was an independent risk factor for mortality (P < 0.05). There was statistically significant decrease in the overall 5-year and 10-year patient survival (P = 0.031) in KT patients admitted to the ICU.
Conclusion
Our study shows that the main reason for ICU admissions was infections especially in late admission. Mortality rate were relatively high and was linked to need for ventilators. Admission to the ICU is usually associated with decrease in the graft and patient survival.