Kidney Week

Abstract: SA-PO1070

Clinical Predictors for the Incidence of Severe Acute Pyelonephritis During Antepartum Based on National Health Examination Data

Session Information

• Diet and Nutrition: Clinical
  October 27, 2018 | Location: Exhibit Hall, San Diego Convention Center
  Abstract Time: 10:00 AM - 12:00 PM

Category: Health Maintenance, Nutrition, and Metabolism

• 1302 Health Maintenance, Nutrition, and Metabolism: Clinical

Authors

• Ko, Gang Jee, Korea University College of Medicine, Guro Hospital, Seoul, Korea (the Republic of)

Gang Jee Ko,

• Ahn, Shin-Young, Korea University College of Medicine, Guro Hospital, Seoul, Korea (the Republic of)

Shin-Young Ahn,

• Cho, Eunjung, Korea University College of Medicine, Guro Hospital, Seoul, Korea (the Republic of)

Eunjung Cho,

• Kwon, Young-Joo, Korea University College of Medicine, Guro Hospital, Seoul, Korea (the Republic of)

Young-Joo Kwon,

• Cho, Geum joon, Korea University College of Medicine, Guro Hospital, Seoul, Korea (the Republic of)

Geum joon Cho,

Background

Acute pyelonephritis is common during pregnancy, and increases the risk of maternal and fetal outcome. However, it has not been clearly revealed yet which demographic and clinical characteristics are associated with the incidence of acute pyelonephritis during pregnancy

Methods

Study data were collected from the Korea National Health Insurance Claims Database of the Health Insurance Review and Assessment Service. Women who had delivery between 2010 and 2014 in Korea and received health examination prior within one year of pregnancy were enrolled. A model of multivariate logistic regression analysis was performed to evaluate the risk of acute pyelonephritis during pregnancy.

Results

The mean±SD age of the overall cohort of 370,248 women was 31±4 years. The incidence of acute pyelonephritis (APN) treated under hospitalization was 2,526 patients (0.7%). In multivariate logistic regression analysis, younger age (OR 0.93 for every 5 years increase, 95% CI, 0.88-0.98), previous history of APN within one year of pregnancy (OR 9.37, 95% CI, 8.26-10.64), and abnormal results of health examination such as high fasting glucose without history of diabetes (>100mg/dL, OR 2.06, 95% CI, 1.41-2.99) and proteinuria (OR 1.81, 95% CI, 1.16-2.83) were associated with increasing risk of acute pyelonephritis during pregnancy.

Conclusion

Certain maternal demographic and clinical characteristics were associated with the incidence of acute pyelonephritis during pregnancy, and they should be monitored closely during antenatal care.