ASN represents more than 21,000 kidney health professionals working to help people with kidney diseases and their families. Comprised of all of ASN's focus areas, the ASN Alliance for Kidney Health allows the society to continue its growth and work towards the goal of a world without kidney diseases.
The latest Nephrology Self-Assessment Program (nephSAP) issue, Volume 23: Issue 2 (Jun 2024): Electrolytes and Acid-Base Disorders is now available online.
RE: Membranous nephropathy 39 minutes ago
In my experience . resistance to therapeutic action of RTX consequent to anti-HACA antibodies is very uncommon. Failure to deplete CD19+ B cells af...
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RE: Membranous nephropathy 1 hour ago
I have the same opinion like 14 days ago. I would go with o anti-CD38 Ab if you are still convinced it is pure MN. Reading through the case initi...
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RE: is it indicated to undergo parathyroidectomy? 2 hours ago
Dr. Venkat p, I can certainly understand why a low bone density (particularly in cortical bone ) might be a useful non -invasive parameter to emplo...
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RE: is it indicated to undergo parathyroidectomy? 3 hours ago
Dr. Gorbatkin: Thanks for posting this table.,Indications for PTX in primary HPT listed therekin appear very appropriate. Dr. Glassock: I note th...
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RE: is it indicated to undergo parathyroidectomy? 5 hours ago
Do other nephrologists follow guidelines listed below for surgery in asymptomatic primary hyperparathyroidism, or disagree with them? If none of th...
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RE: is it indicated to undergo parathyroidectomy? 9 hours ago
Thank you very much for all the ideas and reflection in this discussion. ------------------------------ Wael Jebur MD, FASN drwaellatif@hotmail....
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RE: is it indicated to undergo parathyroidectomy? 10 hours ago
The words in CAPITAL letters in Dr. Venkat's comments, underscore the relative non-specificity of DEXA scanning in CKD5D and this undermines the ut...
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RE: Tirzepatide In Dialysis Patient 11 hours ago
To my knowledge, there are some who have postulated potential benefits in dialysis patients, and there are some ongoing studies. So far, no evidenc...
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RE: Tirzepatide In Dialysis Patient 11 hours ago
I have used it. Pt lost weight got his BMI under control and got transplanted Effects of Renal Impairment on the Pharmacokinetics of the D...
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RE: Membranous nephropathy 11 hours ago
Appreciate all the input. Follow up labs are: BUN/Cr 16/1.3 (PreviosulyCr 1.01 --> 1.05 --> 0.94) UA pro 3+, blood 2+ Spot urine pr: Cr rat...
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RE: is it indicated to undergo parathyroidectomy? 18 hours ago
Dr. Venkat and Dr.Glassock thank you very much for your last comments, this is exactly what I was trying to suggest in our last discussion about DE...
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RE: Solute diuresis - post obstructive diuresis how long does it last? 1 day ago
Agree to focus on negative fluid balance as blood pressure is under control. I also want to ask about serum potassium levels, since hypokalemia ...
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RE: is it indicated to undergo parathyroidectomy? 1 day ago
Thanks. Great explanation Dr. Venkat. I agree 100%. ------------------------------ Richard Glassock MD, FASN Laguna Woods CA (949) 388-8885 -----...
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RE: is it indicated to undergo parathyroidectomy? 1 day ago
Dr. Jebur: I apologize for not making my point clearly. Recent discussion threads in the ASN Open Forum have suggested that DEXA is best avoided...
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RE: Tirzepatide In Dialysis Patient 1 day ago
Side effects of Tirzepatide (particularly nausea) seems to be increased in dialysis patients and the AUC after a fixed dose might be increase compa...
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RE: Tirzepatide In Dialysis Patient 1 day ago
Difficult question. No data (yet) on GLP1RA in dialysis patients Benefits on weight loss, reduction in CVD events, or improvement in mortality unkn...
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Tirzepatide In Dialysis Patient 1 day ago
High all I need your input about using Tirzepatide ln dialysis patient for weight loss in non diabetic patient And also in diabetic dialysis patient
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RE: is it indicated to undergo parathyroidectomy? 1 day ago
Thank you Dr.Venkat, Will kindly rephrase your statement as I am not able to grasp your idea properly. Thank you ---------------------------------...
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RE: is it indicated to undergo parathyroidectomy? 1 day ago
Yes, the high urinary calcium would rule out FHH ------------------------------ Stuart Sprague DO, FASN Director of Research, Division of Nephrol...
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RE: Solute diuresis - post obstructive diuresis how long does it last? 1 day ago
Before my fellowship years I saw a patient with post obstructive diuresis. First 2 days his IVF was set to 1:1 match with urine output. Ur...
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RE: Solute diuresis - post obstructive diuresis how long does it last? 1 day ago
Sorry for being late in discussion but I was to share this case scenario. Before few weeks I was consulted for similar case with post obstructive d...
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RE: Post-partum HELLP v. aHUS 2 days ago
We also have a TMA disease oriented group at Mayo. We meet regularly to discuss difficult cases. ------------------------------ Nelson Leung MD ...
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RE: is it indicated to undergo parathyroidectomy? 2 days ago
With a high 24 hour urinary calcium isn't FHH completely ruled out? ------------------------------ Satish Balan MD DM DNB Nephrologist Kerala I...
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RE: Post-partum HELLP v. aHUS 2 days ago
The concept that the creation of "virtual teams" to facilitate management of complex case of TMA will have very broad impact across the entire spec...
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RE: Post-partum HELLP v. aHUS 2 days ago
Thanks for the update, Dr. Landry. Encouraging to hear about the pt's response. The concept of developing TMA teams is very close to my heart and s...
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RE: Solute diuresis - post obstructive diuresis how long does it last? 2 days ago
Great pic. Thanks. We need a little humor to lighten up the conversation on this site. ------------------------------ Richard Glassock MD, FASN ...
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RE: Post-partum HELLP v. aHUS 2 days ago
Thank you Dr. Java for this timely review. An update on our patient: Eculizumab administered Tuesday afternoon with peak LDH 3500 now down to 500, ...
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RE: Solute diuresis - post obstructive diuresis how long does it last? 2 days ago
On the lighter side, the visual equivalent: https://www.edvardmunch.org/the-scream.jsp#google_vignette ------------------------------ Sheldon Hir...
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RE: Solute diuresis - post obstructive diuresis how long does it last? 2 days ago
Strong words, but very good advice, in my opinion. ------------------------------ Richard Glassock MD, FASN Laguna Woods CA (949) 388-8885 -----...
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RE: Post-partum HELLP v. aHUS 2 days ago
PLEX and steroids are used if suspicion for TTP is high. In that case, you could PLEX until ADAMTS13 is back. However, these treatments are not ver...
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RE: Solute diuresis - post obstructive diuresis how long does it last? 2 days ago
This scenario makes me want to scream. iatrogenic polyuria, originally was post obstructive appropriately getting rid of salt and water and urea ac...
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RE: is it indicated to undergo parathyroidectomy? 2 days ago
Dr. Jebur, I agree this is very likely primary hyperparathyroidism. However, patients with apparent mild-to-moderate hyperparathyroidism, could pos...
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RE: Solute diuresis - post obstructive diuresis how long does it last? 2 days ago
Dr. Zapata: Convincing your colleagues to abruptly stop full oral + IV fluid replacement may be difficult. Please ask them to limit total fluid int...
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RE: is it indicated to undergo parathyroidectomy? 2 days ago
Dr. Jebur: I am aware that your patient doesn't have CKD/ESKD. Her DEXA-documented osteopenia is most likely due to primary HPT. I was just trying ...
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RE: Post-partum HELLP v. aHUS 2 days ago
Thank you all for the very fruitful discussion One question In such scenario, any role for PLEX/ plasma infusion and /or steroids till we get th...
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RE: is it indicated to undergo parathyroidectomy? 2 days ago
Thanks for your replies. I think what might prompt decision to proceed is the risk of malignant lesion as well --------------------------------- W...
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RE: is it indicated to undergo parathyroidectomy? 2 days ago
And she is post menopausal --------------------------------- Wael Jebur MD, FASN drwaellatif@hotmail.com Dubai ---------------------------------
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RE: is it indicated to undergo parathyroidectomy? 2 days ago
Dear Dr.Venkat renal function is normal and she has no renal reported. --------------------------------- Wael Jebur MD, FASN drwaellatif@hotmail....
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RE: Solute diuresis - post obstructive diuresis how long does it last? 2 days ago
Then I completely agree with Dr. Hirsch. There is usually no need for IV fluids unless you're using them to address a pathologic diuresis (i.e., el...
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RE: IgA Vasculitis in an adult 2 days ago
Dr. Vaidya: Please post today's SCr ASAP. Very interested to see if SCr is continuing to improve following methylprednisolone boluses even before y...
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RE: IgA Vasculitis in an adult 2 days ago
Yes. This should be sufficient. If this is truly a hydralazine Vasculitis, repeated dosing of RTX may not be needed. ---------------------------...
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RE: Monitoring Response After Rituximab 2 days ago
Correct. Don't know for sure about Obi but I want to agree w you because Obi is 'humanized' form of RTX. PremChandran
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RE: IgA Vasculitis in an adult 3 days ago
Thank you everyone for your valuable inputs. Rituximab 1 g x 2 doses 2 weeks apart ? ------------------------------ ChiragVaidya ---------------...
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RE: membranous nephropathy 3 days ago
Dr. Venkat -fully agree with you. But AKI secondary to bilateral RVT was not really a consideration in this case. ------------------------------ ...
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RE: IgA Vasculitis in an adult 3 days ago
Now I understand the significance of the anti-dsDNA antibody and anti-MPO ANCA - this is almost certainly Hydralazine induced Vasculitis superimpos...
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RE: IgA Vasculitis in an adult 3 days ago
Mild petechial lesions in left shin which are fading away. He is on Hydralazine for HTN ( Can cause drug induced lupus) No drug use See renal ...
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RE: membranous nephropathy 3 days ago
Dr. Glassock: I absolutely agree with you that AKI due to bilateral acute RVT or acute RVT in a solitary functioning is very rare. However, if this...
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RE: IgA Vasculitis in an adult 3 days ago
Thanks. Can you provide any more details on the cutaneous findings in this case (*mentioned in the Biopsy Report)? The kidney pathology is consiste...
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RE: IgA Vasculitis in an adult 3 days ago
Can you please post recent creatinine trend? Have you repeated UPr/Cr and/or UAlb/Cr? ------------------------------ K.K. Venkat MD Troy MI (248)...
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RE: Solute diuresis - post obstructive diuresis how long does it last? 3 days ago
The patient's bacteremia has cleared, and their hemodynamics are stable. The continuation of IV fluids is recommended by the primary attending and ...
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