ASN represents more than 21,000 kidney health professionals working to help people with kidney diseases and their families. Comprised of all of ASN's focus areas, the ASN Alliance for Kidney Health allows the society to continue its growth and work towards the goal of a world without kidney diseases.
The latest Nephrology Self-Assessment Program (nephSAP) issue, Volume 23: Issue 5 (Dec 2024): Transplantation is now available online.
RE: Treatment of Sclerotic glomerular disease 14 minutes ago
Ok. Thank you Dr.Glassock for your advice. We would consider the genetic test later. --------------------------------- [Vivian] [Peng] [Dr] [Affi...
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RE: Global glomerulosclerosis vs. FSGS 4 hours ago
Perhaps Dr. Fogo would like to opine on these two cases as focal and global Glomerulosclerosis has been one of her research interests over a number...
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RE: Case For Thought 4 hours ago
I agree with Dr, Venkat. This is what I intended to convey in my post. . Is the patient a male or female. - the posts are contradictatory - but ...
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RE: Global glomerulosclerosis vs. FSGS 4 hours ago
The only thing these two patients have in common is Focal and Global glomerulisclerousis , well in excess of the expected for age. What are the his...
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2025 ASN NMRI Travel Support Award 4 hours ago
ASN is now accepting applications for the 2025 ASN-Network of Minority Health Research Investigators (NMRI) Travel Support award. The Network of...
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RE: Case For Thought 5 hours ago
Deceased donor transplant under eculizumab coverage is an option. ------------------------------ K.K. Venkat MD Troy MI (248) 420 7798 ----------...
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Global glomerulosclerosis vs. FSGS 5 hours ago
I have encountered two patients, both men in their early 30s. One has a SCr of 3.5 mg, normal UAlb/Cr and UPr/Cr and the other had a SCr of 1.5 mg/...
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RE: Case For Thought 6 hours ago
Thanks prof glassock . So she is committed to a lifetime of dialysis ? --------------------------------- Muhammad Soobadar MBChB UK -----------...
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RE: Case For Thought 6 hours ago
With a very high recurrence rate of DDD in allograft kidney transplants (65%-85%), often causing premature graft loss , I would discourage LD trans...
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RE: Low Potassium 9 hours ago
Thanks prof rodby . Curious how do you get rise in potassium of 3 with 40 mmol and ecv 15 litres Best wishes --------------------------------- M...
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Case For Thought 9 hours ago
4 year old male with low c3 , nephrotic syndrome and renal impairment . Kidney biopsy c3 glomerulopathy ( DDD) Genetic studies - novel missense v...
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Central diabetes insipidus with a nephrogenic component? 9 hours ago
Patient, 44 years old, with a history of polyuria and polydipsia for 1 year. Denies other associated symptoms. Relevant medical history includ...
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RE: Immune complex GN in patient with untreated RA 11 hours ago
Over what time period did SCr increase from 1.4 mg to 2.4 - 2.8 mg (if several SCr are available over this period)? How long has SCr been around 2....
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RE: Immune complex GN in patient with untreated RA 14 hours ago
non-lupus full house has a bad prognosis, this is predominantly a membranous pattern and I prefer using a membranous type of IS for membranous patt...
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RE: Low Potassium 15 hours ago
I think urinary K/Cr ratio works, but I would try not to do it close to an infusion, like measuring albuminuria during albumin infusions. 24 hou...
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RE: Immune complex GN in patient with untreated RA 15 hours ago
I have not been able to get all the labs from the rheumatolost yet, but this is what i have: ANA was not quant hep c ab neg cryo neg will c...
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RE: Immune complex GN in patient with untreated RA 15 hours ago
Lupus or "Rupus" (some overlap as suggested), RA can have a pauci immune pattern of GN with or without ANCA as well. As a lumber I would treat this...
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RE: (another) Refractory Minimal Change Disease (Dialysis dependent and I promised patient I would submit) 15 hours ago
Dear Dr Rodby. The patient has a history of rapid deterioration of renal function. In April, creatinine was 2, and within weeks, the condition w...
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RE: (another) Refractory Minimal Change Disease (Dialysis dependent and I promised patient I would submit) 16 hours ago
Could you explain that answer please, in doing so give a short synopsis of how you see this case? thanks ------------------------------ Roger Ro...
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RE: Treatment of Sclerotic glomerular disease 16 hours ago
First patient the IF had some Iga and some lambda , both weak, no kappa, lambda restriction has been reported in IgAN Were there amy mesangial d...
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RE: Treatment of Sclerotic glomerular disease 18 hours ago
Immunosuppressive therapy us not indicated in either patient. I would do genetic testing and manage them conservatively . -----------------------...
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RE: Treatment of Sclerotic glomerular disease 18 hours ago
The EM report of the first patient: A semi-thin section shows one piece of renal cortex containing three sclerotic glomeruli. Some renal tubules ex...
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RE: (another) Refractory Minimal Change Disease (Dialysis dependent and I promised patient I would submit) 20 hours ago
With this clinical evolution typical of rapidly progressive glomerulonephritis, a new biopsy must look for crescents and start plasma exchange imme...
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RE: Immune complex GN in patient with untreated RA 1 day ago
Do you know the RF level, HCV serology , cryoglobulins and ANA?. Low C4 levels have been reported in RA. If you have access to NELL1 and EXTI/II st...
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RE: Low Potassium 1 day ago
Urinary K excretion levels , especially with spot measurements, should not be relied upon to reflect the state of K depletion, if tge samples are o...
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Immune complex GN in patient with untreated RA 1 day ago
The patient is a 78 yoF (caucasian) with rheumatoid arthritis for > 30 years who developed nephrotic syndrome and creatinine increased to 2.4 - 2.8...
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RE: Low Potassium 1 day ago
If someone is having oral or iv potassium replacement for low k and we do urinary electrolytes is it still valid ?and if not how do we correct for ...
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RE: Case 1 day ago
Nephropathy not neuropathy --------------------------------- Muhammad Soobadar MBChB UK ---------------------------------
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RE: Case 1 day ago
Present a while after starting not whole --------------------------------- Muhammad Soobadar MBChB UK ---------------------------------
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RE: Case 1 day ago
Thanks prof glassock. Rivaroxiban 20 mg od. No paracetamol. Rivaroxiban started a while ago 2 years but Aki recent . Haematuria new and macroscopi...
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RE: Dialysate flow rate 1 day ago
Increasing dialysate rate will not do too much more and is a waste of a precious natural resource called fresh potable water. On the other hand, ...
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RE: Dialysate flow rate 1 day ago
This is helpful ------------------------------ Kashif Chaudhry MD Canton MI (248) 943-2986 ------------------------------
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RE: Granulomatous interstitial nephritis 1 day ago
Born in British Columbia and moved to California as a child, has lived here all of his life. Agree the clinical pattern is of profound tubular inju...
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RE: Case 1 day ago
While it was originally called "warfarin nephropathy" this has now been described as anticoagulant nephropathy and NOACs have been reported. ...
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RE: Paternity under Tolvaptan 2 days ago
Thank you for your input. Regards. ------------------------------ Sehsuvar Ertürk, MD Ankara University School of Medicine Department of Nephro...
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RE: Case 2 days ago
Was the hematuria macroscopic or microscopic? What was the dose of paracetamol and rivaroxiban. Any distal features of cholesterol embolism (blue t...
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Case 2 days ago
80 year old Past medical history AF on rivaroxiban , bilateral cataracts and AMRD. Presented to hospital on 27/12/24. He had haematuria . Family do...
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RE: Possible Pd Case 2 days ago
Thanks so much dr Bargman --------------------------------- Muhammad Soobadar MBChB UK ---------------------------------
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RE: Paternity under Tolvaptan 2 days ago
About 5% of male patients with ADPKD are infertile, due to sperm abnormalities. I do not think that Tolvaptan therapy has any benefits or harms for...
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RE: Paternity under Tolvaptan 2 days ago
Given that ADPKD is really a systemic polycystin problem and many organs other than the kidneys can be involved, I found this that may be relevant ...
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RE: Dialysate flow rate 2 days ago
For PD KT/V we use Ideal body weight for V. UpTODate states this is fine for the reasons above. We cannot do this for HD bc KT/V is from the MEASUR...
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RE: Potential Donor with TRPC6 inactivating mutation 2 days ago
Great practice point Dr. Lerman. Genetic testing of potential tecipients awaiting live donor kidney transplants is greatly underutilized at present...
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RE: Potential Donor with TRPC6 inactivating mutation 2 days ago
Completely agree with excluding this donor in view of the positive genetic testing. This is exactly why most genetic experts recommend first testin...
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RE: Membranous Nephropathy And Hypothyroidism 2 days ago
Thank you very much for your valuable input @Roger Rodby @Richard Glassock The patient received Rituximab today, and will follow her anti PLA2R abs...
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RE: Dialysate flow rate 2 days ago
The above is why I listed huge patients as one of the possible exceptions to the quest for some particular kt/v. Increasing blood flow (and, in tur...
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RE: Potential Donor with TRPC6 inactivating mutation 2 days ago
The TRPC6 gene variant here is reported as likely pathogenic. The interesting part here is that the genetic variant has variable penetrance meaning...
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RE: Anyone know what happened to the Innovations in Kidney Education Contest? 2 days ago
Hello, Dr. Topf, Thank you for your post. ASN decided to pause the Innovations in Kidney Content the last couple of years due to declining intere...
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RE: Potential Donor with TRPC6 inactivating mutation 2 days ago
Of course, the donor may harbor other genes or epigenes that modify the expression of the mutated gene, such that she may never manifest tge phenot...
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RE: Dialysate flow rate 3 days ago
The Watson formula greatly overestimates the V term in KT/V urea calculation in massively Obese subjects . A bioelectrical impedance value for V is...
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RE: Dialysate flow rate 3 days ago
A one size fits all approach does not work in hemodialysis but that is what CMS seems to favor. I am not sure what Kt/V minimum target is appropria...
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