ASN represents more than 21,000 kidney health professionals working to help people with kidney diseases and their families. Comprised of all of ASN's focus areas, the ASN Alliance for Kidney Health allows the society to continue its growth and work towards the goal of a world without kidney diseases.
The latest Nephrology Self-Assessment Program (nephSAP) issue, Volume 23: Issue 2 (Jun 2024): Electrolytes and Acid-Base Disorders is now available online.
RE: proteinuria. ? timing of biopsy. 2 hours ago
One remaining unexplained issue is the disparity in kidney size. . Renal ultrasound can be notoriously problematical for determining kidnet size in...
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RE: proteinuria. ? timing of biopsy. 8 hours ago
Thanks. Possible that one APO1 high risk allele might be implicated as a second "hit" for FSFS in severe nephron under-endowment, tgat is almost ce...
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RE: proteinuria. ? timing of biopsy. 10 hours ago
G1 only , one risk Allel. CUBN is heterzygous. ------------------------------ Khaldoun Soudan MD alexandria LA ------------------------------
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RE: Hypertension urgency 10 hours ago
I guess these cases meet the "definition" of Pseudochromocytoma , a very vague (and rare) diagnosis, at best. Is it listed in ICD 10? -----------...
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RE: Hypertension urgency 12 hours ago
Thank you for your replies. Both of the patients denied having any drug intake, they were not on regular medications. They denied consuming any ove...
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RE: Nephrotic Syndrome with PIGN Picture 14 hours ago
I don't know of any evidence that Cyclophosphamide , RTX or PLEX is effective and safe in cases like your patient. But lack of evidence is not equi...
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RE: Nephrotic Syndrome with PIGN Picture 15 hours ago
C3NeF and anti FB & FH auto-antibodies are not available in the local laboratories, they should be sent abroad. I don't think she can afford it. C...
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RE: Hypertension urgency 17 hours ago
Is the patient orthostatic? Pheos are often orthostatic from volume depletion related to pressure natiruesis. See attached. -----------------...
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RE: Post-partum HELLP v. aHUS 17 hours ago
From Dr Chang: Roger, Thanks for reaching out about that challenging post-partum pt. That sounds very concerning for (complement-mediated) atyp...
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RE: Post-partum HELLP v. aHUS 17 hours ago
Hi Dr. Landry, I was alerted to this post by a colleague asking for me to respond since I have interest in TMA/aHUS with a genetics background. ...
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RE: Post-partum HELLP v. aHUS 18 hours ago
@Anthony Chang (U of C nephro-pathologist) posits that many of these TMA syndromes are all congenital complement deficiency mediated and that there...
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RE: Post-partum HELLP v. aHUS 18 hours ago
No signs of SLE or anti-phospholipid syndrome? Based on the information you have shared , I would be giving strong consideration to employing Eculi...
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Post-partum HELLP v. aHUS 18 hours ago
Good morning. I appreciate the opinions of this audience regarding 39-year-old female currently 4 days status post urgent C-section with persistent...
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RE: Hypertension urgency 18 hours ago
Great idea. If catecholamines and abdominal CT are unremarkable, then this "diagnosis" seems very reasonable. ------------------------------ R...
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RE: Nephrotic Syndrome with PIGN Picture 19 hours ago
Initially, "C3 was slightly consumed." Dr. Youssef: Serial C3 levels? Is microhematuria persisting? I assume SCr/eGFR remain normal although prot...
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RE: proteinuria. ? timing of biopsy. 19 hours ago
Interesting findings. Were two high risk APOL1 risk alleles ( G1, G2 ) present?Was the CUBN mutation homozygous or heterozygous? What was the plasm...
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RE: Hypertension urgency 19 hours ago
Pseudopheochromocytoma? Please see following review: https://pubmed.ncbi.nlm.nih.gov/35000148/ ------------------------------ K.K. Venkat MD T...
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RE: Nephrotic Syndrome with PIGN Picture 19 hours ago
Compatible with C3GN. Infection related GN, less lijely. You might do a C3NeF and an anti-Factor B and anti factor H.For now , therapy with MMF and...
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RE: Hypertension urgency 19 hours ago
Any history of drug abuse (especially cocaine) in either case.? I assume that catecholamine studies were unremarkable and no adrenal or retroperito...
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RE: 17q12 deletion syndrome 20 hours ago
work my way up to 30 mg/d slowly, following K. ------------------------------ Roger Rodby MD, FASN Professor of Medicine Rush University Medical ...
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Hypertension urgency 20 hours ago
Hi I came across couple of cases wherein two patients were brought to the emergency units in two different times with complains of headache or fe...
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RE: Nephrotic Syndrome with PIGN Picture 21 hours ago
To update you, this is the EM report. She has clinically worsened, still edematous and proteinuria 9 gm on predn. & MMF. -------------------------...
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RE: Adjunctive acetazolamide therapy for the treatment of Bartter syndrome 1 day ago
No deafness Pending genetic --------------------------------- Mohamed Mahmoud MBBS NEPHROLOGIST MOH Egypt 00965 51377736 --------------------...
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RE: 17q12 deletion syndrome 1 day ago
How high would you go on Amiloride dose? Thanks! ------------------------------ Khaldoun Soudan MD alexandria LA ------------------------------
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RE: proteinuria. ? timing of biopsy. 1 day ago
Update: Genetic testing was done and interstingly showed: 1- Positive APOL1 heterozygous risk Allel 2-autosomal recessive CUBN, associated wit...
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RE: AKI and low C3 1 day ago
Thank you for your input. urine without activity/abnormalities and renal US is normal. ------------------------------ Khaldoun Soudan MD alexand...
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Women in Nephrology Fellows' Initiative 1 day ago
WIN has 2 exciting opportunities for Fellows!! 1) The application deadline for the WIN Hsiao Leadership fellowship has been extended to July...
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RE: Adjunctive acetazolamide therapy for the treatment of Bartter syndrome 1 day ago
Does the patient have sensorineural deafness. This is the only form (very rare ) of Bartter Syndrome with spontaneous Serum Bicarbonate levels this...
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RE: Adjunctive acetazolamide therapy for the treatment of Bartter syndrome 1 day ago
I don't have a good answer - I hope some experts in Bartter syndrome chime in with some opinions on the rationale for treating metabolic alkalosis ...
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RE: 12-year-old child on Dialysis 1 day ago
Did the "secondary" evaluation include looking for MAHA? The focal and global glomerulosckerisis indicates chronic disease which may mean irreversi...
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RE: Adjunctive acetazolamide therapy for the treatment of Bartter syndrome 1 day ago
Thank you prof. Glassock So in such patient if potassium normal we can leave hime by HCO3 50 as no trial showed target bicarbonate ------------...
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RE: 12-year-old child on Dialysis 1 day ago
did they di a congo red (FMF).long shot Sounds like a primary tubulointerstitial disease with secondary glomerular dropout , but NO proteinuria? ...
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12-year-old child on Dialysis 1 day ago
Appreciate your opinion on the following pediatric case: 12-year-old male Location: Middle East Medical history: Previously healthy, born full-ter...
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RE: Paucimmune GN with Low Complements In Young Patient 2 days ago
I would not get too concerned about the hypo complementemia in this case. I think it is likely a part of the spectrum of laboratory abnormalities s...
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RE: Paucimmune GN with Low Complements In Young Patient 2 days ago
Dr. Venkat, unfortunately no EM was done. --------------------------------- Hayder Aledan MD, FASN Assistant Professor Basra Nephrology and Transp...
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RE: Renal Function in 55 yo male 2 days ago
Thank you Professor Glassock No history of low endowement. I will check the urine concentrating capacity. Regards Omar Kaisar ---------...
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RE: Renal Function in 55 yo male 2 days ago
Thank you Dr Rodby. The gentleman is lean and fit. I have attached the urine result below. We had discussed genetic testing. We havent pursued it y...
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RE: Renal Function in 55 yo male 2 days ago
Dear Dr Venkat Thank you so much. The cystatin C level was done close to the time of the creatinine level. Previous cystatin level was done at...
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RE: Adjunctive acetazolamide therapy for the treatment of Bartter syndrome 2 days ago
Can someone please explain to me why one would target therapy to correct the elevated plasma bicarbonate in Bartter Syndrome? What are the expected...
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RE: Paucimmune GN with Low Complements In Young Patient 2 days ago
Dr Venkat But there is no C3 or c1q staining on IF Surprising serum levels very low Any explanation for that Perhaps repeat levels Thanks ----...
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RE: Transplant Question 2 days ago
s: CDC crossmatch is less sensitive than the flow cytometry crossmatch. A positive CDC crossmatch indicates a higher level of donor-specific antibo...
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RE: Fibrillary GN 3 days ago
Thank you Dr. Glassock and Dr. Rodby for a prompt response. Hep C negative. Age appropriate Cancer screening is negative. SPEP/UPEP -unremarkable -...
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RE: Adjunctive acetazolamide therapy for the treatment of Bartter syndrome 3 days ago
Also as I read the pharmacologic concentration of Sando tablet, each tablet contain 600 mg KCl and 400 mg KHCO3 giving a total of 12 mmol K salts s...
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RE: Adjunctive acetazolamide therapy for the treatment of Bartter syndrome 3 days ago
NSAIDs use address the pathophysiology of Bartter syndrome as those patients have high PGE2 resulting from uncoupled tubuloglomerular feedback as C...
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RE: Primary hyperaldosteronism 3 days ago
Thank you ASN forum members for all the responses. So screening for Pheo Latest Reference Range & Units 02/12/24 09:18 03/07/24 1...
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RE: Fibrillary GN 3 days ago
I would seriously consider enrolling this patient in the Obinutuzumab For Fibrillary GN being conducted at the Mayo Clinic (under direction of Lada...
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RE: Post TX TMA 3 days ago
De novo PT-TMA is more common than recurrent PT-TMA so I agree with Dr. Lerman that after rule out CMV infection and ABMR, this TMA may be due to C...
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RE: Post TX TMA 3 days ago
Since you did several changes Plex/ dc Tac/ start rapamune hard to know which is responsible for clinical improvement. -----------------------...
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RE: Adjunctive acetazolamide therapy for the treatment of Bartter syndrome 3 days ago
NSAID therapy will be long life I don not now is it safe? --------------------------------- Mohamed Mahmoud MBBS NEPHROLOGIST MOH Egypt 00965 5...
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RE: management of PLA2R negative membranous nephropathy 3 days ago
Hi, Dr. Aledan, Thank you so much for your suggestions. will try to see if can get the serum antibodies first. I will need to discuss with pathol...
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