Abstract: FR-PO945
Incidence of Glomerulonephritis and Clinical Outcomes of Kidney Biopsy Patients at the National and Transplant Kidney Institute, 2016-2022
Session Information
- Glomerular Diseases: Potpourri
October 25, 2024 | Location: Exhibit Hall, Convention Center
Abstract Time: 10:00 AM - 12:00 PM
Category: Glomerular Diseases
- 1402 Glomerular Diseases: Clinical, Outcomes, and Therapeutics
Author
- Estolas, Melanie Timboy, National Kidney and Transplant Institute, Quezon City, National Capital Region, Philippines
Background
Glomerulonephritis remains a predominant cause of end stage kidney disease and is potentially reversible but entails a kidney biopsy for definitive diagnosis, management decisions and prognostication. There is limited data on incidence of glomerular diseases in the Philippines, and a national kidney biopsy registry is lacking for the years 2016 and onwards.
Methods
A total of 2249 patients who had native kidney biopsy at NKTI from 2016-2022 were identified and a retrospective review of their chart records, laboratory results and kidney biopsy findings was done, with a follow up for at least 12 months.
Results
The median age for kidney biopsy was 34 years with a higher female prevalence (56.16%). Primary glomerulonephritis comprised 74.17% of cases and secondary GN for 23.5%. IgA nephropathy at 45.86% and FSGS at 19.78 were the most common for primary GN. For secondary GN, Lupus nephritis was the most prevalent at 56.7%. IgAN had the highest incidence of complete and partial remission. Progression to ESRD requiring dialysis was almost similar for IgAN and FSGS.
Conclusion
IgA nephropathy is still the most prevalent type of primary glomerulonephritis in this single center study, while Lupus nephritis is the most common secondary GN. A significant overall improvement in kidney function and proteinuria was noted on follow up.